6/15/2023 0 Comments Haematology manual sop![]() For example, immature cells, because of their relatively large size, tend to concentrate at the feathered edge, so their distribution may be less random across a slide than in a fluid state. This discrepancy may occur not only because of significant differences in the total cell count but also because of other factors affecting the peripheral blood smear. ![]() Therefore, as noted in the question, a low proportion of IGs detected by automated differential may not be reflected in a random 100-cell manual differential. The total number of cells counted for differentials is, of course, much higher by automated methods (30,000 cells on Sysmex platforms, for example) compared with a manual method (standardly 100 cells). ![]() December 2019-The immature granulocyte (IG) fraction-metamyelocytes, myelocytes, and promyelocytes-can be quantified on modern peripheral blood analyzers as part of the six-part automated differential of the white blood cell count. ![]() How do you report the presence of the immature granulocytes? A. But when the 100-cell differential was performed, the immature granulocytes were not reflected. When reviewing a smear, we observed scattered (rare) immature granulocytes during a scan.
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